Ganciclovir Therapeutic Drug Monitoring: A Case Series

A Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs

Immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. This variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. Drug monitoring is widely practiced ...

monitoring cyclosporine absorption: a step beyond therapeutic drug monitoring

Therapeutic drug monitoring of ganciclovir for postnatal cytomegalovirus infection in an extremely low birth weight infant: a case report

BACKGROUND Ganciclovir is a therapeutic choice for extremely premature infants with severe postnatal cytomegalovirus disease, but little is known about its optimal dose size and dosing interval for them. CASE PRESENTATION We treated an extremely premature female infant with postnatal cytomegalovirus infection with intravenous administration of ganciclovir since 49 days of life (postmenstrual ...

therapeutic drug monitoring

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Near-fatal drug toxicities in newborn babies: A Case Series

Background: Neonates are highly vulnerable to drug toxicities because of their age-related limitations in drug metabolisms and renal excretion. Lack of the knowledge and/or education for medical professionals about the right dose administration and the lack of neonate-specific formulations are the additional dilemmas. Cases Presentation: Here, we reported six neonates presented with severe ...